At birth, our innate immune system is unexperienced but well-established. Snoeck noemt het onomwonden technische nonsens die voor een niet-wetenschapper moeilijk te doorprikken zijn. Follow More from Medium Mehek Kapoor in. Indeed, antibodies (Abs) produced by our own immune system can be considered self-made antiviral antibiotics, regardless of whether they are part of our innate immune system (so-called natural Abs) or elicited in response to specific pathogens (resulting in so-called acquired Abs). The notion that this is somehow a problem relies on the unsupported claim that a natural infection would be better equipped to kill SARS-CoV-2. That. Is het Russisch volk goedgelovig en volgzaam? Noting how quickly Dr. Vanden Bossches letter was embraced by antivaxxers, Frei then writes: But from my experience as a former long-time medical writer and journalist (1988-2016) particularly a four-month stint with media-relations giant FleishmanHillard in 1994 (yes, Ive worked for the dark side) this has all the hallmarks of a drug-company astroturf campaign. There's even grift likely involved! Dr. Geert Vanden Bossche, is a world-class certified expert in microbiology and infectious disease, who also has a Ph.D. in virology and a longstanding career in human vaccinology. Natural Abs are not germ-specific whereas acquired Abs are specifically directed at the invading pathogen. Specifically, Im referring to the abuse of evolutionary theory by antivaxxers to claim that vaccines select for more deadly variants of pathogenic viruses and bacteria, making mass vaccination programs dangerous or even potentially catastrophic. Ik heb een lijst van professoren die mijn bezorgdheden delen en zal deze publiceren. p.528-531. It has been observed that over time Mareks disease virus has become more virulent, and this has been attributed classically to a leaky vaccine effect. Iedereen kan een wilde theorie verzinnen, maar daarna moet je dat wel wetenschappelijk staven.. Ten derde wijst hij erop dat de gezondheidsrisico's van Covid-19 voor gezonde kinderen, zoals ziekenhuisopname, verwaarloosbaar klein zijn en dat vaccinatie vanuit dat oogpunt voor die groep geen enkele zin heeft. Seriously, as a vaccine expert, how is it that Dr. Vanden Bossche does not know this? In verschillende video's op YouTube waarschuwt de Belgische wetenschapper Geert Vanden Bossche voor een ramp nog groter dan de coronacrisis zelf. Up to this point, at its core and leaving aside minor variations, Dr. Vanden Bossches argument about COVID-19 vaccines and COVID-19 is pretty close to exactly the same argument that Wakefield fallaciously made about MMR and measles. So its not surprising that Dr. Vanden Bossches letter reminds me of Andrew Wakefields warning about the MMR vaccine. Wij staken ons licht op bij verschillende vakgenoten en hun oordeel over zijn stelling is eensluidend: Technische nonsens. As we explain below, this scenario is speculative, scientifically flawed, logically inconsistent, and belied by actual data. Een vorige versie van dit stuk meldde dat Geert Vanden Bossche een onbestaande functie bij de Universiteit Gent claimde op LinkedIn. Even if it were evolving resistance, once again, the answer would be to reformulate the vaccine in order to include the altered antigens, the same conclusion made when considering the possibility that B. pertussis was evolving resistance or that evolutionary drift was leading to the predominance of strains not covered by the vaccine. This will, indeed, require large vaccination campaigns. Vanden Bossche has been able to avoid allegations of peddling such a cure at least in the credulous anti-vaccine community because his resume legitimately includes stints at companies or initiatives involved in vaccine development, including The Bill and Melinda Gates Foundation. There is, indeed, compelling scientific evidence that these cells play a key role in facilitating complete elimination of Covid-19 at an early stage of infection in asymptomatically infected subjects. [1] In 2018 he was elected president of the Society of International Economic Law (SIEL). So, why then should there be a major concern using these vaccines to fight Covid-19? De inhoud is, tenzij anders aangegeven, beschikbaar onder. Relatiedeskundige Rika Ponnet beantwoordt de vraag van de week: "Moeder-dochterrelaties zijn meest complexe relaties Dan toch geen Europees verbod op benzine- en dieselwagens? De tekst is beschikbaar onder de licentie. Central to the concept in his article, published via the in-house journal of the American Association of Physicians and Surgeons (AAPS), an organization I like to refer to as the John Birch Society of medical societies given its penchant for conspiracy theories and pseudoscience, was that the MMR vaccine, by selecting for more aggressive measles strains, could result in a sixth extinction event. Menu. The resulting type of immune response is unprecedented and licenses the host immune system to readily eliminate infection or to cure disease across a broad range of unrelated pathogens and/ or mammalian species. Transformation is rapidly becoming the key to survive as an organsisation. Er zijn overigens niet veel mutaties nodig voor een bacterie om resistent te worden tegen een antibioticum. Maar een virus zou een hele resem mutaties moeten doormaken om het afweersysteem van ons lichaam te omzeilen. Hij was daarbij kritisch over de veiligheid van een ebolavaccin. 10.8K. Leroux-Roels duikt tijdens ons gesprek in de databank clinicaltrials.com, waar alle wetenschappelijke studies geregistreerd worden. Speaking with McGill University's Office for Science and Society, Dr. Paul Offit, a doctor and vaccine scientist who serves as director of the Vaccine Education Center at the Children's Hospital of Philadelphia, explained that no matter where one is or was quarantined, you are still constantly exposed to microorganisms challenging your immune system. Integendeel: die strategie helpt net om een epidemie onder controle te krijgen. (Truly, those were simpler times.). Ultimately, most vaccines are based on a recombinant spike protein sequence. Indien hij gelijk krijgt natuurlijk. This problem will be exacerbated, he claims, because people who have been vaccinated (and/or social distancing and staying inside during the pandemic) will be less capable of fighting off those strains than someone who has not been vaccinated. He has a long list of companies and organizations he's worked with on vaccine discovery and preclinical research, including GSK, Novartis, Solvay Biologicals, and Bill & Melinda Gates Foundation. 721. Volgens hem kan dat vooral gebeuren wanneer mensen slechts n dosis krijgen, of te lang moeten wachten op een tweede. As a scientist I do not usually appeal to any platform of this kind to make a stand on vaccine-related topics. This inevitably leads to enhanced natural selection and adaptation of more invasive immune escape variants, 2/4 6 37 Agnes van den Bossche (c.1435 - c.1504), Flemish painter. It means either "from the woods" or "from Den Bosch ". Hij kreeg achteraf de wind van voren van het parlement, maar 'antivaxer' Geert Vanden Bossche vertelde woensdag in het debat over vaccinatieplicht niet uitsluitend onzin. However, as we age, we will increasingly face situations where our innate immunity (often called the first line of immune defense) is not strong enough to halt the pathogen at the portal of entry (mostly mucosal barriers like respiratory or intestinal epithelia). Variants are "a thing to keep an eye on," Saad Omer, an epidemiologist who serves as director of the Yale Institute for Global Health, told us in a phone interview. The world is changing and the change is gaining speed ! De Vlaamse veearts Geert Vanden Bossche pleit ervoor om alle coronavaccinaties stop te zetten. Geert Vanden Bossche, PhD Geert Vanden Bossche, PhD, DVM, is a vaccine research expert. Het werkt op verschillende fronten tegelijk. The role of spike protein variability inT cell immunity is likely to be elucidated in experimental studies in the next few months; a priori, the enhanced repertoire of T cell epitopes makes the loss of cytotoxic activity or recognition improbable. This is a very confused argument. He does apparently have some history working on vaccines. (Indeed, thus far, it appears that this is the case.) NK cells are pathogen destroying cells that are part of the innate immune system. Because, among other things: 1) Neither in the original March 6 piece nor his March 13 follow-up does Vanden Bossche provide any direct, non-theoretical evidence that this is happening; 2) The natural antibodies that are produced after encountering a pathogen are only a small part of a quick, effective and broad-based first-line immune-system defense known as innate or passive immunity which in fact largely comprises other components; and 3) Vanden Bossche downplays the effectiveness of the antibodies our bodies naturally produce as part of the second-line (adaptive) part of the immune system that also has served us extremely well for millennia. So-called leaky vaccines are vaccines that prevent disease, but do not appreciably slow transmission of the pathogen. This is why I decided to already post a summary of my findings as well as my keynote speech at the recent Vaccine Summit in Ohio on LinkedIn. Het vaccin is God niet. Because his proposed solution appears to be a fantasy, its effect would be to stop vaccinations completely and replace them with nothing. His argument sounds a lot like an argument Andrew Wakefield once made for MMR. Basically, its a race against evolution to get as many people as possible vaccinated before the virus can evolve resistance to the vaccine, and were fortunate that, contrary to Bossches claim, SARs-CoV-2 does not mutate very fast for an RNA virus. There you have it, the lone scientific maverick who is the only one willing to speak out about against a horror being perpetrated by conventional medicine and science that they dont want you to know about or discuss, a horror thats so urgent that he must speak now. Basically, Dr. Vanden Bossches open letter is a mess that directly channels Andrew Wakefield. He also points out that there is new research challenging the previous dogma that leaky vaccines always select for more virulent strains of pathogen and cannot produce herd immunity. Several variations of the originally isolated strain have emerged since the start of the pandemic, and some of these variants are more infectious, contagious, or possibly deadly. He also states that hes worked with GAVI: The Vaccine Alliance and the Bill and Melinda Gates Foundation, although searching the websites, I could find no reference to him other than a report written by him and others to GAVI about progress on an Ebola vaccine. Such claims are generally an offshoot of another favorite antivaccine claim, namely that the diseases being vaccinated against are so innocuous that vaccinating against them is overkill and allowing infection and natural herd immunity to occur is better, a trope that has also been resurrected about COVID-19, a disease thats killed well north of 500K people in just the US in a little over a year. Vanden Bosche argues that widespread vaccination will put evolutionary pressure on the viruses to develop adaptations in this case changes to the spike protein that allows the virus to infect cells in a way that will allow it to escape the vaccine's protection. Ill refer you to Nirenbergs demolition of Dr. Vanden Bossches nonsense about innate immunity, as he explains why its nonsense better than I can. Er is al vaak gevaccineerd tijdens een epidemie, en dat heeft nog nooit tot grote sterfte geleid. The way to avoid this purported calamity, Vanden Bossche asserts, is for scientists to pay more attention to his own invention a "universal vaccine" that uses the body's innate immune system to kill SARS-CoV-2. RNA viruses like SARS-CoV-2 do mutate. Hes also conflating innate immune responses with specific immune responses induced by either infection or vaccination. They shall only be contradicted by science. Well, similar to the rules applying to classical antimicrobial antibiotics, it is paramount that our self-made antiviral antbiotcs [sic] are made available in sufficient concentration and are tailored at the specific features of our enemy. As those have stronger affinity for the pathogen (e.g., virus) and can reach high concentrations, they can quite easily outcompete our natural Abs for binding to the pathogen/virus. "Hoe zou dat ook moeten werken? Hij beweert dat je door veel te vaccineren tijdens een pandemie een nieuwe en veel dodelijkere vorm van het virus kan creren. 60 ID:Ofxf3u990 ? But wait, says Dr. Vanden Bossche. In an effort to sidestep this self-evident solution, Vanden Bossche seems to have made up a second mechanism to stoke fear over COVID-19 vaccines. Na enkele dagen van stilte nam Vanden Bossche vandaag zijn camera en reageerde met een video op hetgeen in de media is verschenen. There are 10+ professionals named "Geert Van Den Bossche", who use LinkedIn to exchange information, ideas, and opportunities. After all, if a human vaccine lets deadlier versions of a disease flourish, that is all the more reason to be protected from those deadly strains. A recent review article suggests that immune escape by variants of SARS-CoV-2 is a possibility, but one that hasnt been definitively observed or demonstrated yet: So is there cause for concern?
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